How and why pancreatitis moves quickly to the death?
Acute pancreatitis may in some cases be to cause serious complications. They often change very quickly and life-threatening to lead to death. If the mechanism is explained, the management of complications is difficult to master ...
The pancreas is an organ located behind the stomach, it is essentially a gland involved in
- Digestion (production of digestive enzymes)
- The regulation of sugar metabolism by its endocrine function (production of insulin, and glucagon)
Pancreatitis is a disease characterized by inflammation of the pancreas. It differs essentially:
- Acute pancreatitis
- Chronic pancreatitis
Acute pancreatitis is characterized by a rapid and brutal damage the pancreas. It is a condition that evolves very fast to complications, which are serious and life threatening. The most known and common causes are excessive and chronic alcohol consumption and gallstones. However, other causes are not dismissed as side effects of certain drugs, or infectious origins.
In 70% of cases, acute pancreatitis is benign and can be cured after treatment for several days. In 30% of cases, there is a serious and severe pancreatitis, often fatal even during treatment.
Severe acute pancreatitis is often associated with the achievement of several other bodies found in the first week, requiring care in a service intensive care unit or an intensive care unit. This organ failure is related to the same pathophysiological mechanism of pancreatitis, which can lead to multi visceral necrosis. Necrosis of the pancreas itself is a serious complication, life-threatening to the patient.
Several mechanisms may be responsible for the rapid onset of cardiac, pulmonary and renal complications:
- Trypsin and trypsinogen are substances involved in digestion and secreted by the pancreas. In pancreatitis, these substances, not evacuated, exacerbate the onset of local inflammation of the pancreas, which can lead to inflammation and visceral multi necrosis.
- Inflammatory reaction blood causes pancreatic release of several inflammatory cytokines such substances as well as pancreatic enzymes. These substances are responsible for the formation of micro disseminated thrombosis in the blood vessels, which can lead to bleeding.
Several factors are used to assess the severity of acute pancreatitis: age, obesity, organ failure (cardiac, neurological, renal, respiratory, ...) ... Several evaluation methods such as Ranson score, the score "SOFA" Balthazar score, also allow the doctor to make a prognosis. These scores take into account mainly the patient's age and biological criteria reflecting the operation of the various systems and organs (blood glucose, AST, hematocrit, blood urea nitrogen, calcium, oxygen saturation, radiographic examination of the pancreas, ...).
The pancreas is an organ located behind the stomach, it is essentially a gland involved in
- Digestion (production of digestive enzymes)
- The regulation of sugar metabolism by its endocrine function (production of insulin, and glucagon)
Pancreatitis is a disease characterized by inflammation of the pancreas. It differs essentially:
- Acute pancreatitis
- Chronic pancreatitis
Acute pancreatitis is characterized by a rapid and brutal damage the pancreas. It is a condition that evolves very fast to complications, which are serious and life threatening. The most known and common causes are excessive and chronic alcohol consumption and gallstones. However, other causes are not dismissed as side effects of certain drugs, or infectious origins.
In 70% of cases, acute pancreatitis is benign and can be cured after treatment for several days. In 30% of cases, there is a serious and severe pancreatitis, often fatal even during treatment.
Severe acute pancreatitis is often associated with the achievement of several other bodies found in the first week, requiring care in a service intensive care unit or an intensive care unit. This organ failure is related to the same pathophysiological mechanism of pancreatitis, which can lead to multi visceral necrosis. Necrosis of the pancreas itself is a serious complication, life-threatening to the patient.
Several mechanisms may be responsible for the rapid onset of cardiac, pulmonary and renal complications:
- Trypsin and trypsinogen are substances involved in digestion and secreted by the pancreas. In pancreatitis, these substances, not evacuated, exacerbate the onset of local inflammation of the pancreas, which can lead to inflammation and visceral multi necrosis.
- Inflammatory reaction blood causes pancreatic release of several inflammatory cytokines such substances as well as pancreatic enzymes. These substances are responsible for the formation of micro disseminated thrombosis in the blood vessels, which can lead to bleeding.
Several factors are used to assess the severity of acute pancreatitis: age, obesity, organ failure (cardiac, neurological, renal, respiratory, ...) ... Several evaluation methods such as Ranson score, the score "SOFA" Balthazar score, also allow the doctor to make a prognosis. These scores take into account mainly the patient's age and biological criteria reflecting the operation of the various systems and organs (blood glucose, AST, hematocrit, blood urea nitrogen, calcium, oxygen saturation, radiographic examination of the pancreas, ...).
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