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HIV and AMP: all couples can hope to have a child


A couple of two affected by the AIDS virus can expect to have a child with medically assisted procreation (MAP), said Dr. Juliette Guibert (Cochin Hospital, Paris), at a press conference in margin of the 30th National Day of CNGOF (French National College of obstetricians), held in conjunction with the World Day against AIDS.
Possibility of birth through the AMP
Since the advent of HAART in 1996, which amended the profile of HIV patients, considered a chronic, rather than fatal disease quickly, doctors began in 1998 to consider more readily associated with the MPA issue HIV.
"Two research protocols have been carried out in France, after the work done in Italy and Belgium: one at Cochin Hospital, one in Toulouse, in men infected with HIV, separating the seminal fluid sperm, the latter being free of any viral presence. Overall, sixty couples was treated at Cochin and the same proportion in Toulouse with since no contamination has been reported "success raises the reproductive specialist .
Then the order of 10 May 2001 authorized the practice routinely in centers with a completely separate lab to accommodate gametes from infected people, the aim being to prevent mixing of materials and contamination.
Procreate, protect and overcome infertility
"The MPA in a couple affected by HIV has two goals, said Dr. Guibert procreate without sacrificing protection methods in the couple and overcome infertility if any man and / or woman are infected."
The method proves safe for all HIV-negative partner and children, if the man is infected.
"In the HIV-positive woman, a self-insemination can be performed at home, consisting of a collection of sperm in a condom without spermicide (reports are necessarily protected) using a needleless syringe, then reinjected into the vagina without the need for an aseptic environment. Semen can be collected after masturbation into a clean container, non-sterile, before being reintroduced into the vagina, "describes the gynecologist, while noting the possibility of insemination center if the couple wishes (even with a GPA IVF infertility).
When both partners are infected, we must continue to protect the sex, she says, to avoid surcontamination because viruses differ from one individual to another, developing in each agency or resistance mutations . In this situation, IVF is immediately considered.
Since 2001, 500 children born
"In France, informs Dr. Guibert, 500 children were born in the ART centers, about 150 per year and by 1000 annual cycles insemination or in vitro fertilization technique (IVF): it is a heavier processing ( requiring ovulation stimulation, injections three weeks a month and a puncture eggs), but is indispensable if elements of infertility are superimposed to the HIV disease. Indeed, the virus is often associated with other sexually transmitted infections such as chlamydia, caused severe salpingitis and tubal obstructive pathologies. "
If a child born to an HIV-negative mother can not be infected (serological tests are now performed in this situation), AMP does not prevent possible transmission from an infected mother to her child. "The contamination rate is still below 1% (or even much lower, versus 20 to 25% in case of natural evolution of the infection without treatment) if the viral load remains undetectable in women. Nevertheless, the patient was treated the last trimester of pregnancy, childbirth and post-natal period, and the child is always at birth in six weeks, "said the specialist.

According to her, as with any off HIV GPA must not only be in a relationship for two years to qualify, but, in the case of HIV-positive women, regardless of their age ("especially if it is the partner who is infected "because age would have a greater impact on ovarian function in the presence of HIV, it probably had an effect on fertility):" So it is important not to delay pregnancy if the desire child 'is confirmed and the right conditions, "she recommends.

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Author: Mohammad
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