Limit children's exposure to domestic allergens is not enough to reduce the risk of asthma or allergy
The only reduce exposure of infants to domestic allergens is not enough to reduce the incidence of respiratory allergic diseases and asthma in children five years shows published in the journal "Thorax" British study .
For twenty years, the exposure of young children to allergens at home is suspected to play a major role in the occurrence of respiratory allergies, wheezing and asthma, suggesting that reduced levels of allergens household could reduce the incidence of these diseases, recall Dr. Paul Cullinan and colleagues from the National Heart and Lung Institute in London.
In their study, the researchers followed 625 children from birth to the age of 5.5 years.
At baseline, parents were tested at different skin allergens and were questioned about their possible respiratory symptoms. Then, when the children reached the age of two months, different levels of household allergens were measured in dust collected at home. Finally, during the last year of follow-up, parents were asked about any respiratory symptoms occurred in their children, who then underwent a skin allergy test.
The results of these analyzes revealed that 10% of participants were young, at the age of 5.5 years, sensitized to cat allergens or mites in dust. This means that their tests showed that they react to these allergens, but not necessarily imply that they develop clinical manifestations (asthma, eczema ...) in their presence. In addition, 7% of children with atopic wheezing.
The overall analysis did not show a link between exposure to allergens and allergic sensitization or wheezing.
However, a closer examination of the data showed an association between the risk and the level of exposure to allergens: the risk of allergy and wheezing increases for low allergen levels and decreases for higher rates, with boost when the father is allergic or when the child is the first of the siblings.
These results suggest that the link between exposure to indoor allergens and the risk of atopy, wheezing or asthma is complex, involving interactions between genes and the environment more important than you think the authors conclude.
Household allergens may play a role in the development of asthma and respiratory allergies but at a level likely to be extremely low, they say.
This study also suggests that a strategy only to reduce the levels of exposure to indoor allergens will have no major impact on the incidence of respiratory allergies and asthma, they add.
For twenty years, the exposure of young children to allergens at home is suspected to play a major role in the occurrence of respiratory allergies, wheezing and asthma, suggesting that reduced levels of allergens household could reduce the incidence of these diseases, recall Dr. Paul Cullinan and colleagues from the National Heart and Lung Institute in London.
In their study, the researchers followed 625 children from birth to the age of 5.5 years.
At baseline, parents were tested at different skin allergens and were questioned about their possible respiratory symptoms. Then, when the children reached the age of two months, different levels of household allergens were measured in dust collected at home. Finally, during the last year of follow-up, parents were asked about any respiratory symptoms occurred in their children, who then underwent a skin allergy test.
The results of these analyzes revealed that 10% of participants were young, at the age of 5.5 years, sensitized to cat allergens or mites in dust. This means that their tests showed that they react to these allergens, but not necessarily imply that they develop clinical manifestations (asthma, eczema ...) in their presence. In addition, 7% of children with atopic wheezing.
The overall analysis did not show a link between exposure to allergens and allergic sensitization or wheezing.
However, a closer examination of the data showed an association between the risk and the level of exposure to allergens: the risk of allergy and wheezing increases for low allergen levels and decreases for higher rates, with boost when the father is allergic or when the child is the first of the siblings.
These results suggest that the link between exposure to indoor allergens and the risk of atopy, wheezing or asthma is complex, involving interactions between genes and the environment more important than you think the authors conclude.
Household allergens may play a role in the development of asthma and respiratory allergies but at a level likely to be extremely low, they say.
This study also suggests that a strategy only to reduce the levels of exposure to indoor allergens will have no major impact on the incidence of respiratory allergies and asthma, they add.
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