AnorectaleAnorectic
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Anorexigenic or appetite suppressants are substances reducing hunger.
They are used in dieting.
Currently the most dangerous (some amphetamines) were withdrawn from the
market.
The use of these drugs should be very careful because they are not
recommended for individuals with a psychiatric history, epileptics, the
arterial hypertension, the hyperthyroid (Basedow) Alcohol and tobacco.
You have to be very careful and do not use associated with certain medications
(particularly MAOIs)
These drugs should only be used for short courses because it is a kind
of addiction that may increase the dose, which is completely unrealistic and
dangerous.
We must prevent sports that taking these drugs can cause a positive
reaction in doping control.
Include: the Dinintel the Fenproprex the Moderaton the Prefamone,
Tenuate Dospan which are amphetamine.
The Isomeride has a specificity and action on feeding behavior by
inhibiting carbohydrate consumption while maintaining the protein consumption.
It does not have any hypertensive effect of psychostimulant effect.
It is cons-indicated in cases of Glaucoma and should not be used with
MAOIs.
The Ponderal which acts on the satiety center, without neuro exciting
effect, reduces food intake, mobilizes fats.
It is cons-indicated in cases of Glaucoma and should not be combined
with MAOIs.
In reality, these appetite suppressants are not necessary, as it is true
that motivation is the originator if any weight loss. However, at the beginning
of a diet, the more difficult to bear period, they can be a good supplement.
The drug agency has informed all doctors risk of long-term prescription
appetite suppressant or appetite suppressants. Indeed, it was noted a higher
risk (multiplied by 4) pulmonary hypertension is a disease of fatal outcome.
The study was made shows the factors favoring the occurrence of this disease:
- More than 3 months of an anorectic use
- Combination of several anorectics
- Obesity with body mass index less than 30,
- Hypertension earlier.
The recorded accidents have occurred during treatment.
Although the risk is moderate but there can be no question of making the
slightest risk only for aesthetic purposes. That is why now, the anorectic
administration will that second-line after failure of a dietary correct treatment
(see LOSE REASONABLY).
This administration will be in case of overt obesity with a body mass
index greater than 30. This index is calculated by dividing weight by height in
meters squared. Example a man weighing 110 pounds 1.80m 1.80 x1, 80 = 3.24 and
110 divided by 3.24 = 33.95, so obesity license.
The body mass index can be considered as:
- Below 22 you are dealing with a thin,
- From 23.5 to 26.5 normality
- From 26.5 to 27.5 mild obesity,
- From 27.5 to 29 degree of obesity,
- Over 30 overt obesity.
The use will be reduced to three months.
It will never be prescribed appetite suppressants 2 simultaneously.
All masterful in anorectic basic requirements must meet the requirements
of the Decree of the Ministry of Health.
Anorexigenic affected by this measure are: anorex the dinintel,
fenproporex the incital, Isomeride the modératon, the weight, the préfamone the
Dospan Tenuate.
In June 1995, the National Commission for pharmacovigilance consider the
risk-benefit ratio of this therapeutic class in its medical indications.
In October 1995, the drug agency has modified the device of prescription
appetite suppressants which can no longer be prescribed first-line general
practitioners, the initial prescription is reserved for specialized hospital
services in diabetology, endocrinology, metabolic diseases and medicine
internally.
The GP can make a renewal order and the patient will get the
pharmacist's drug on the presentation of the initial hospital prescription and
renewal of the general order.
In addition, prescription fenfluramines (Isomeride and Ponderal) may be
maintained in patients "responders" (those in which the benefits of
drug therapy is obvious after a course of three months).
However, for amphetamine and related, the prescription is limited to 3
months from April to June cures weeks because of the risk of DEPENDENCE.
Author: Mohammad
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