What treatments against AIDS?
It eThe
anti-viral
The goals of
treatment with anti-viral are:
- Slowing the
spread of viruses to reduce the viral load (amount of virus in the body).
- Maintain
effective in the fight against the virus CD4 lymphocytes.
Nucleoside
reverse transcriptase inhibitors (NRTIs)
Action: Prevents
processing of viral RNA proviral DNA
Side Effects:
Risk of kidney toxicity
Non-nucleoside
reverse transcriptase inhibitors (NNRTIs)
Action: Prevents
processing of viral RNA proviral DNA
Side Effects:
May cause skin rashes. Cons-indicated in pregnant women
Protease
inhibitors
Mode of Action:
Inhibits maturation of new virus and block the infection of other cells
Side effects
interactions with other drugs
Integrase
inhibitors
Action: Prevents
touch proviral DNA to the DNA of the host cell
Side effects:
dizziness, digestive disorders, liver toxicity
Fusion
inhibitors
Mode of Action:
Inhibits fusion of the virus with the host cell and blocks viral entry into the
cell
Side effects:
muscle pain, lung disease.
These treatments
and enable a longer life expectancy and improves the patient's quality of life.
HAART
It is the combination
of three drugs against the virus (3 nukes) whose main action is to slow the
growth. The side effects are transient, but in no case should encourage the
patient to stop taking the drug in order to ensure its effectiveness.
These side
effects are usually related to intolerance to 3 concomitant medications. The
most common are headaches, digestive disorders (nausea and vomiting), loss of
appetite, fatigue, and skin rashes.
The quadruple
Based on the
same principle as the combination therapy, it is used to improve the
effectiveness of antiviral immunity against the virus itself.
Researchers have
shown that the combination of several drug molecules avoids resistance
virales.xiste several strains of anti-viral types that differ in their mode of
action
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