Crohn's disease: medication
The treatment is usually prescribed by a gastroenterologist. The GP's role is to monitor the evolution of the disease (course of treatment, monitoring the occurrence of complications) for.
Medication
Treatment is given according to the intensity and location of the signs of the disease. All drugs introduced in the treatment of Crohn's disease should be prescribed in a doctor's prescription.
Drug treatment is specific to each patient and is individualized. For this patient-physician collaboration is required and it is more convenient for the doctor to assess the effectiveness of drugs based on data provided by the patient. It is therefore advisable for patients with Crohn's disease to note changes daily and signs of the disease include:
- The number of stool consistency (liquid, soft, strong, bloody mucus)
- The characteristics of abdominal pain: frequency, duration, intensity
- The presence or absence of loss of appetite
- The types of foods that trigger or aggravate the signs
- The curve of daily weight
The aminosalycilés (5-ASA or mesalamine, olsalazine, sulfasalazine)
Action: Anti-inflammatory effect on the intestinal mucosa. With minor outbreaks of the ileum and colon
Side effects: Nausea, vomiting, headache. Great medical monitoring of renal function
Corticosteroids (prednisolone, prednisone, hydrocortisone)
Action: Anti-inflammatory. In case of moderate or severe flare
Side Effects: A long-term weight gain, insomnia, calcium deficiency, osteoporosis, acne
Immunosuppressants (cyclosporine, azathioprine, 6-mercaptopurine)
User Action: Change and removes excessive immune response to the intestinal mucosa. In case of severe hospital. For maintenance therapy
Side effects: Nausea, vomiting. Malaise, hypotension, rash, fever, joint and muscle pain
Immunomodulators (TNF-alpha injection: infliximab, adalimumab)
Action: Fight against inflammation and the action of TNF-alpha. If cons-indications of corticosteroids and immunosuppressants. Used primarily in hospitals. Also used in maintenance treatment.
Side effects: immediate Frequent: anaphylactoid (pruritus, fever, chills, headache, shortness of breath, ...)
The anti-diarrheal
Action: To stop diarrhea.
Side effects: worsening of inflammation in some people
Antibiotics (metronidazole, ciprofloxacin)
Mode of action: Sometimes used if abscesses
Antispasmodics, analgesics (acetaminophen)
Mode of Action: Against abdominal pain or for joint pain
Outside attacks, it is highly recommended to break the dietary restrictions and adopt a normal, balanced and varied diet to prevent deficiency symptoms and undernutrition.
The reintroduction of these foods will gradually and as tolerated by the patient, introduce one food per day, starting with the low-fiber vegetables (carrots, zucchini, eggplant, beets ...) prefer to form mixed vegetables, consume fruit compotes.
General measures
Rest.
Increase the intake of vitamins (vitamin A, C, D, E, K, folic acid, vitamin B12), minerals (calcium, copper, magnesium, zinc, selenium), and especially iron.
Stop smoking: it has been shown that smoking cessation during flares of Crohn's disease can have a remission of signs.
Compensate for losses caused by diarrhea and vomiting by drinking enough water throughout the day.
Avoid taking Ibuprofen and Aspirin including nonsteroidal anti-inflammatory drugs. These drugs are harmful to the digestive mucosa, so they can aggravate the signs or even trigger an inflammatory flare.
Medication
Treatment is given according to the intensity and location of the signs of the disease. All drugs introduced in the treatment of Crohn's disease should be prescribed in a doctor's prescription.
Drug treatment is specific to each patient and is individualized. For this patient-physician collaboration is required and it is more convenient for the doctor to assess the effectiveness of drugs based on data provided by the patient. It is therefore advisable for patients with Crohn's disease to note changes daily and signs of the disease include:
- The number of stool consistency (liquid, soft, strong, bloody mucus)
- The characteristics of abdominal pain: frequency, duration, intensity
- The presence or absence of loss of appetite
- The types of foods that trigger or aggravate the signs
- The curve of daily weight
The aminosalycilés (5-ASA or mesalamine, olsalazine, sulfasalazine)
Action: Anti-inflammatory effect on the intestinal mucosa. With minor outbreaks of the ileum and colon
Side effects: Nausea, vomiting, headache. Great medical monitoring of renal function
Corticosteroids (prednisolone, prednisone, hydrocortisone)
Action: Anti-inflammatory. In case of moderate or severe flare
Side Effects: A long-term weight gain, insomnia, calcium deficiency, osteoporosis, acne
Immunosuppressants (cyclosporine, azathioprine, 6-mercaptopurine)
User Action: Change and removes excessive immune response to the intestinal mucosa. In case of severe hospital. For maintenance therapy
Side effects: Nausea, vomiting. Malaise, hypotension, rash, fever, joint and muscle pain
Immunomodulators (TNF-alpha injection: infliximab, adalimumab)
Action: Fight against inflammation and the action of TNF-alpha. If cons-indications of corticosteroids and immunosuppressants. Used primarily in hospitals. Also used in maintenance treatment.
Side effects: immediate Frequent: anaphylactoid (pruritus, fever, chills, headache, shortness of breath, ...)
The anti-diarrheal
Action: To stop diarrhea.
Side effects: worsening of inflammation in some people
Antibiotics (metronidazole, ciprofloxacin)
Mode of action: Sometimes used if abscesses
Antispasmodics, analgesics (acetaminophen)
Mode of Action: Against abdominal pain or for joint pain
Outside attacks, it is highly recommended to break the dietary restrictions and adopt a normal, balanced and varied diet to prevent deficiency symptoms and undernutrition.
The reintroduction of these foods will gradually and as tolerated by the patient, introduce one food per day, starting with the low-fiber vegetables (carrots, zucchini, eggplant, beets ...) prefer to form mixed vegetables, consume fruit compotes.
General measures
Rest.
Increase the intake of vitamins (vitamin A, C, D, E, K, folic acid, vitamin B12), minerals (calcium, copper, magnesium, zinc, selenium), and especially iron.
Stop smoking: it has been shown that smoking cessation during flares of Crohn's disease can have a remission of signs.
Compensate for losses caused by diarrhea and vomiting by drinking enough water throughout the day.
Avoid taking Ibuprofen and Aspirin including nonsteroidal anti-inflammatory drugs. These drugs are harmful to the digestive mucosa, so they can aggravate the signs or even trigger an inflammatory flare.
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