Crohn's first pregnancy

When Crohn's disease is progressive thrust at the time of conception, the risk of spontaneous abortion is important. In quiescent period, the risk remains the same as for the rest of the population.

Crohn's disease is not conducive to the occurrence of malformations in the fetus.

Premature birth and fetal growth retardation are rare, but can occur if exacerbation during pregnancy, hence the importance of strict supervision.

Women who have undergone surgery for their disease are more vulnerable to complications than others.

Patients with Crohn's disease are not more sterile than women in the rest of the population in quiescent periods.

Salazopirine treatment has no impact on ovarian function, as well as corticothérapique treatment (except perhaps for the latter if the doses are important).

Treatment should be continued in women who become pregnant. The treatment did not affect fetal development.

By cons, it should be noted that the father in the salazopirine treatment can affect fertility. It may be desirable where possible to stop taking salazopirine in the father before conception.

The use of immunosuppressive drugs in women is a problem that will be solved by the doctor.

The majority of women with Crohn's disease give birth normally.

Sometimes the anorectal disease location will advise a caesarean section.

Pregnancy does not seem to impact on the appearance of a potential surge if pregnancy begins during a quiescent period.

The percentage thrust is 20% as in other non-pregnant women. Any relapses occur either in the first trimester of pregnancy or during the three months following the birth.

By cons, if conception occurs during a period of evolutionary thrust in a third of cases the disease will worsen in another third the disease progresses at least partially positive, and finally for the last third of the disease will not be changed by pregnancy.

Thrust during pregnancy, especially in the first quarter, its own gravity: the risk of spontaneous abortion in particular. During the remainder of the pregnancy, it can induce fetal growth retardation, premature birth.

Remains the problem of contraception in woman with Crohn's disease. Oral contraceptives may be prescribed without a problem unless thrust where the risk of venous thrombosis increases.

The IUD is cons-indicated, primarily due to an anti-inflammatory therapeutic potential by glucocorticoid.

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