Hemochromatosis and cirrhosis
Hereditary hemochromatosis is a genetic disease characterized by the
deposition of iron in several organs: the liver, skin, heart, pancreas, ...
The disease is secondary to a genetic mutation. Hemochromatosis affects
more women and occurs frequently at the age of 40 years.
Manifestations of hemochromatosis
Hemochromatosis is changing very slowly over several years.
First the stage, there is a simple accumulation of iron in the body.
At a more advanced stage, signs of iron overload appear:
- Persistent Fatigue
- Joint pain especially at the wrists and hip
- Change the color of the skin is called "browning". The face,
the joints become grayish
- Changing the structure of the skin scaly, with hair loss and hair.
At an advanced stage, complications arise in the organs concerned.
- Impaired liver function leading to the development of cirrhosis
- Deterioration of the function of the heart: heart failure
- These complications are usually associated with diabetes secondary to
a lack of control of blood glucose (blood sugar) in the pancreas.
mechanisms
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